Chrome recently got some support for extensions to access the downloads API. The designer of this API at Google kindly informed us about it.
It now seems possible to do a rudimentary, albeit stripped down version of DownThemAll!, using Chrome’s new capabilities. Advanced features, like segmented downloads, proper checksumming, resuming etc. still do not seem feasible due to technical limitations. However, stuff like filters + OneClick seems to be within reach now. Basically, this new API enables extensions to use the Chrome download manager, but doesn’t give control over the request, data streams and/or low-level details themselves.
This still doesn’t mean you can expect a Chrome version anytime soon, if ever.
Right now there are simply more pressing priorities like getting 3.0 out of the door, and maybe doing a Firefox for Android version.
Having said all that, it should be noted that I’m still very much a mozilla fanboi… in the light of recent revelations maybe more than ever.